Semaglutide injection cost can look confusing because most pharmacies quote monthly carton pricing while patients think in weekly shots. In 2026, branded semaglutide injection cost is usually in the $1,000+ monthly range before coverage, while compounded programs often land below $400 per month.
Reviewed by GoGLP1 Medical Review Board (Clinical Review Team) · Last reviewed May 30, 2026
| Source | Date | Unit | Range | Notes |
|---|---|---|---|---|
| Wegovy/Ozempic retail survey | 2026-05-30 | Per injection equivalent | $225 - $397 | Derived from monthly brand pricing |
| Compounded provider disclosures | 2026-05-30 | Per injection equivalent | $21 - $100 | Monthly bundle divided by 4 |
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| Provider | Price | Meds | Score | |
|---|---|---|---|---|
| Hims Best Value | $199 /mo all-in | SemaTirz | 9.1 | Visit → |
| Ro Best Access | $199 /mo starting | Sema | 8.8 | Visit → |
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There is no universal single-shot price. Most sellers package semaglutide monthly, then effective per-shot cost is derived by dividing total monthly all-in cost by four doses.
It is often lower on a cash-pay basis, but quality controls and bundled services differ by provider and pharmacy model.
Most plans communicate copay/coinsurance at fill level (monthly supply), not per shot.
Start with our <a href="/cost/semaglutide-cost/">semaglutide cost hub</a>, then cross-check <a href="/cost/semaglutide-cost-per-month/">per-month costs</a> and <a href="/cost/compounded-semaglutide-cost/">compounded program costs</a> before choosing a program.